Charles Darwin's worries about possible adverse effects of inbreeding in his family seem to have been justified, according to a study described in the May 2010 issue of BioScience. Darwin married his first cousin, Emma Wedgwood, and his mother, Susannah Wedgwood, was the daughter of third cousins. The study, which extended to 25 families including 176 children, found a statistical association between child mortality and the inbreeding coefficient of individuals in the Darwin/Wedgwood dynasty.
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